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All lanes will be re opened by July 31. All detours will be posted. Access to all residences and businesses will be maintained throughout construction. ADVANCE FOR USE SATURDAY, MAY 13, AND THEREAFTER In this April 28, 2017, photo, Lee Ann Wentzel, center, superintendent of the Ridley School District, speaks with Kim Holdredge, left, and Sarah Messina during a graphic design class at Ridley High School in Folsom, Pa. School districts in Pennsylvania counties near Philadelphia have moved faster than the rest of the state, and the nation, in growing the roster of female school superintendents. Out of the 61 school districts in Bucks, Chester, Delaware and Montgomery counties, 21 districts are run by women, or 34 percent, compared to less than 29 percent of school districts statewide.
Vitamin A in the form of retinoic acid is essential for gene transcription. Retinol is taken up by the cell where it is oxidized to retinaldehyde (by retinol dehydrogenases), which is then oxidized to give retinoic acid. The conversion of retinal to retinoic acid is irreversible and the process is therefore tightly regulated because retinoic acid functions as a ligand for nuclear receptors.
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